Network Pharmacology-Based Prediction and Verification of the Targets and Mechanism for Panax Notoginseng Saponins against Coronary Heart Disease

Figure 2

The whole framework of targets prediction and verification. ADME properties of PNS were first evaluated and then potential treatment targets of PNS against CHD were predicted through identifying common genes. Next, GO function, KEGG pathway, gene coexpression, and topology analysis were performed to predict key targets and their gene function and pathways. Finally, cell experiment was conducted to verify the selected targets and underlying mechanism.