Network Pharmacology-Based Prediction and Verification of the Targets and Mechanism for Panax Notoginseng Saponins against Coronary Heart Disease

Figure 8

Topology analysis of the coexpression network. Figure (a) was the analysis of degree centrality and Figure (b) was k-core decomposition. Green rectangles were common genes which meant query terms. Yellow rectangles were genes associated with query terms in the above coexpression network. The gray edges stand for the interactions among different genes. Gene with more edges had larger rectangle size and the size corresponded to its degree in the coexpression network. Larger size indicated higher degree. The three subnetworks in Figure (b) were all extracted from Figure (a).

(a)

(b)