Evidence-Based Complementary and Alternative Medicine / 2019 / Article / Tab 2

Research Article

Hypoglycemic and Toxic Effect of Morus mesozygia Leaf Extract on the Liver and Kidneys of Alloxan-Induced Hyperglycemic Wistar Rats

Table 2

Results showing reduction in glucose levels from the 0 to 4th hour during the experiment.

Extract/control doseMean glucose level at 0 hour ± SD (mg/dl) value (ANOVA)Mean glucose level at 4th hour ± SD (mg/dl) value (ANOVA)Mean glucose reduction from 0 to 4 hours (mg/dl)Mean glucose reduction from 0 to 4 hours (%)

Days 1–4  200 mg393.8 ± 27.230.991273 ± 16.230.012236.21
400 mg312 ± 16.220.053297.2 ± 31.230.77261.7514.72
800 mg381.6 ± 19.340.495386.2 ± 23.450.58446.8810.05
Gliben408.2 ± 42.110.006261.6 ± 11.430.84159.7535.48
Dmcont455 ± 34.220.009472 ± 33.230.0084−12.2−6.42

Days 5–8200 mg371.5 ± 14.230.552231 ± 18.350.15058.2515.38
400 mg266 ± 23.120.300242.2 ± 11.560.0850.6528.03
800 mg386.33 ± 10.120.029416 ± 22.230.0016109.6737.23
Gliben334.67 ± 25.30.439196.67 ± 27.120.99068.1724.14
Dmcont76 ± 6.870.75376 ± 11.50.9622.553.19

Days 9–14200 mg234 ± 29.230.996236 ± 24.230.93610.533.32
400 mg73 ± 13.020.55843.4 ± 13.650.70320.1131.16
800 mg163 ± 25.230.62929.3 ± 15.310.605116.4465.67
Gliben285 ± 23.340.0042199.3 ± 35.530.29862.1738.85
Dmcont82.8 ± 14.920.11478.2 ± 12.120.0150.330.367

Note that the rats in the Dmcont group died of hyperglycemia. Gliben = diabetic-induced rats that received glibenclamide; Dmcont = diabetic-induced rats that received normal saline; SD = standard deviation. Statistically significantly different ().

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