Research Article

Hypoglycemic and Toxic Effect of Morus mesozygia Leaf Extract on the Liver and Kidneys of Alloxan-Induced Hyperglycemic Wistar Rats

Table 3

Effect of M. mesozygia extract on various biochemical parameters tested.

Nmcont200 mg/kg400 mg/kg800 mg/kgGliben

TT protein26.10 ± 3.5623.90 ± 0.9514.47 ± 9.75#21.73 ± 1.4226.83 ± 1.55
Albumin55.95 ± 3.6546.85 ± 2.6736.74 ± 5.6941.72 ± 3.6448.41 ± 8.75
TAGs1.20 ± 0.781.75 ± 0.301.32 ± 0.551.30 ± 0.122.19 ± 0.90
Cholesterol3.23 ± 0.862.34 ± 3.362.65 ± 0.881.85 ± 0.902.78 ± 0.50
AST252.60 ± 25.33257.43 ± 23.66418.07 ± 19.21386.60 ± 32.22277.27 ± 18.11
ALT228.93 ± 7.67248.27 ± 12.73381.70 ± 13.67339.83 ± 19.87280.73 ± 22.43
Creatinine27.03 ± 18.9236.73 ± 2.8137.57 ± 4.8842.67 ± 10.8045.30 ± 11.07
Urea12.20 ± 2.5820.46 ± 7.0122.21 ± 3.2523.03 ± 9.1613.60 ± 1.41

Significantly different in comparison with normal control (). #Significantly different in comparison with the standard drug ().