Study on Pharmacokinetic and Bioavailability of Tamarixetin after Intravenous and Oral Administration to Rats

Table 5

Pharmacokinetic parameters of tamarixetin after intravenous and oral administration (n = 6).

Parameters	Intravenous (2 mg/kg)	Oral administration (20 mg/kg)
Tmax (h)	0.03 ± 0.00	0.61 ± 0.36
Cmax (ng/mL)	967.93 ± 899.16	49.72 ± 38.31
AUC(0–24 h) (ng/mL·h)	134.29 ± 74.53	163.63 ± 72.29
AUC(0–∞) (ng/mL·h)	138.63 ± 75.43	226.08 ± 122.53
T1/2 (h)	0.03 ± 0.01	9.68 ± 9.45
MRT(0–24 h) (h)	3.07 ± 2.54	6.81 ± 3.10
MRT(0–∞) (h)	4.21 ± 3.15	15.42 ± 10.43