Research Article

Systemic Pharmacological Approach to Identification and Experimental Verification of the Effect of Anisi Stellati Fructus Extract on Chronic Myeloid Leukemia Cells

Figure 4

Changes in the p210Bcr-Abl protein levels treated with ASFE or imatinib (IM). K-562 cells were treated with (a) ASFE (2 μg/mL) or (b) IM (2 μmol) for increasing time periods (0–16 h). The p210Bcr-Abl protein steady-state levels in the total lysates were analyzed by western blotting. Relative protein levels versus controls (beta-actin) were determined by densitometry. Data are the mean ± SD of three independent experiments (; ).
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