Systemic Pharmacological Approach to Identification and Experimental Verification of the Effect of Anisi Stellati Fructus Extract on Chronic Myeloid Leukemia Cells
Table 2
The 10 CML-related compounds of Anisi stellati fructus.
Molecule name
MW
OB (%)
Caco-2
DL
HL
Astragalin
448.41
14.03
ā1.34
0.74
N/A
CHEBI:7
136.26
45.2
1.84
0.04
11.44
(+)-Catechin
290.29
54.83
ā0.03
0.24
0.61
2-Methyl-N-phenylmaleimide
187.21
87.36
0.77
0.06
2.93
Kaempferol
286.25
41.88
0.26
0.24
14.74
Honokiol
266.36
60.67
1.43
0.15
2.88
Luteolin
286.25
36.16
0.19
0.25
15.94
Salicylic acid
138.13
32.13
0.63
0.03
12
(R)-Linalool
154.28
39.8
1.33
0.02
6.48
Quercetin
302.25
46.43
0.05
0.28
14.4
MW: molecular weight; OB: oral bioavailability; Caco-2: Caco-2 permeability; DL-2: drug likeness; HL: drug half-life.