Systemic Pharmacological Approach to Identification and Experimental Verification of the Effect of Anisi Stellati Fructus Extract on Chronic Myeloid Leukemia Cells

Table 2

The 10 CML-related compounds of Anisi stellati fructus.

Molecule name	MW	OB (%)	Caco-2	DL	HL
Astragalin	448.41	14.03	−1.34	0.74	N/A
CHEBI:7	136.26	45.2	1.84	0.04	11.44
(+)-Catechin	290.29	54.83	−0.03	0.24	0.61
2-Methyl-N-phenylmaleimide	187.21	87.36	0.77	0.06	2.93
Kaempferol	286.25	41.88	0.26	0.24	14.74
Honokiol	266.36	60.67	1.43	0.15	2.88
Luteolin	286.25	36.16	0.19	0.25	15.94
Salicylic acid	138.13	32.13	0.63	0.03	12
(R)-Linalool	154.28	39.8	1.33	0.02	6.48
Quercetin	302.25	46.43	0.05	0.28	14.4

MW: molecular weight; OB: oral bioavailability; Caco-2: Caco-2 permeability; DL-2: drug likeness; HL: drug half-life.