Sensitive Biomarker Analysis of Xue-Fu-Zhu-Yu Capsule for Patients with Qi Stagnation and Blood Stasis Pattern: A Nested Case-Control Study

Table 1

Baseline characteristics of the study participants.

Variable	Response group (n = 5)	Nonresponse group (n = 5)	Placebo group (n = 5)
Sex, n
Male	3	4	3
Age, yr
Mean age (SD)	49.80 ± 6.68	43.80 ± 18.32	42.60 ± 13.22
Race, n
Han	5	5	5
Body-mass index^‡	21.39 ± 3.79	22.90 ± 0.56	24.34 ± 4.10
Severity of QS&BS pattern^§	34.40 ± 10.11	31.60 ± 6.03	34.00 ± 5.34
Self-reported coexisting illness, n (%)
Atherosclerosis	1	0	2
Digestive system disease	3	1	0
Reproductive system disease	3	3	1
Osteoarthritis	1	2	1
Hypertension	0	1	1
Diabetes	0	0	0
Routine medications, n (%)
Antiplatelet drugs	0	0	1
Antihypertensive drug	0	1	1
Statins	0	0	0
Oral hypoglycemic drugs	0	0	0

XFZYC = Xue-Fu-Zhu-Yu Capsules; QS&BS = Qi Stagnation and Blood Stasis. Plus-minus values are mean ± SD unless otherwise noted. ^‡Body mass index is the weight in kilograms divided by the square of the height in meters. ^§Severity of QS&BS pattern is assessed by the scores of the items in diagnostic criteria for QS&BS pattern. Scores range from 0 to 51, with higher scores indicating more severe pattern of diagnosis.