Pilose Antler Extracts (PAEs) Protect against Neurodegeneration in 6-OHDA-Induced Parkinson’s Disease Rat Models

Figure 3

PAEs upregulated the levels of DOPAC/DA and HAV/DA in CSF and striatum of PD rats model. (a) 6-OHDA increased DOPAC/DA and HAV/DA in CSF of rats, while 60 mg/kg·d and 180 mg/kg·d PAEs administration decreased DOPAC/DA and HAV/DA in CSF. (b) 6-OHDA increased DOPAC/DA and HAV/DA in striatum of rats, while 60 mg/kg·d and 180 mg/kg·d PAEs administration significantly decreased DOPAC/DA and HAV/DA in striatum (p<0.05 versus model, p<0.01 versus model).

(a)

(b)