Pilose Antler Extracts (PAEs) Protect against Neurodegeneration in 6-OHDA-Induced Parkinson’s Disease Rat Models

Figure 7

PAEs increase GAP-43 and NF-H expression levels in the SNc and striatum of 6-OHDA induced PD rats. GAP-43 and NF-H expression after 6-OHDA administration was detected in the SNc (a) and striatum (b). The expression of GAP-43 and NF-H in SNc after administration with 60 mg/kg·d and 180 mg/kg·d PAEs (a) and striatum (b) increased remarkably. Expression was comparable to 10 mg/kg·d Madopar, especially in the 180 mg/kg·d PAEs administered rats.