Chromatography Based Metabolomics and In Silico Screening of Gymnema sylvestre Leaf Extract for Its Antidiabetic Potential

Table 2

UPLC-MS fingerprinting profile of hydroalcoholic extract of G. sylvestre.

Metabolites	m/z	Name	Class of compound	Reference
M1	350.15	Andrographolide	Labdane triterpenoid	BML80745
M2	367.23	Curcumin	Flavonoid	TY000081
M3	457.17	(-)-Epigallocatechin gallate	Polyphenol cds	TY000083
M4	293.2	Gingerol	Terpenoids	CO000211
M5	267.14	3-Hydroxy-3′-methoxyflavone	Flavonoids	BML80385
M6	351.23	Ajmalicine	Indole alkaloids	FIO00001
M7	277.2	Ascorbic acid magnesium phosphate	Vitamin	PubChem CID:101614363
M8	147.14	Conduritol	Polyphenol cds	PubChem CID: 136345
M9	365.21	Isopentenyl-Adenine-7-glucoside	Pyridine alkaloids	CE000239
M10	251.15	(3aR)-(+)-Sclareolide	Terpenoids	BML80075
M11	303.07	Dihydroquercetin	Flavonoids	BML81120
M12	349.22	Strychnine_N_Oxide	Labdane diterpenoid	CO000416
M13	275.3	Eserine		KO008958
M14	323.2	Quinine	Quinidine alkaloid	BML82035
M15	230.27	7-Diethylamino-4-methylcoumarin	Coumarin	SM884302
M16	335.24	Berberine	Isoquinoline alkaloids	KO008886
M17	316.31	Capillarisin	Sesquiterpnoids	TY000038
M18	336.24	Lobeline	Piperidine alkaloid	BML81620
M19	365.17	Isopentenyl-Adenine-7-glucoside	Pyridine alkaloids	CE000239
M20	413.29	S,R-Noscapine	Benzylisoquinoline alkaloid	CE000163
M21	291.18	Karanjin	Steroidal alkaloid	BML81520
M22	277.24	Linolenic acid	Steroidal alkaloid	BML81605
M23	333.22	Strychnine	Labdane diterpenoid	WA000648
M24	302.33	Hesperetin	Flavonoids	BML81380
M25	337.25	8-Geranyloxy psoralen	Furanocoumarin	BML80640
M26	318.32	Myricetin	Flavonoids	TY000149
M27	275.22	Eserine		KO008958
M28	301.16	Hematoxylin	Neoflavonoids	BML81375
M29	319.25	Coptisine	Benzo[c]phenanthridine alkaloids	TY000106
M30	149.05	Methionine	Sulphur containing amino acid	CE000452
M31	382.46	Dihydrozeatin-9-beta-D-glucoside	Purine nucleosidee	PR020117
M32	279.25	Linoleic acid	Unsaturated fatty acids	EQ331601
M33	365.29	Isopentenyl-Adenine-7-glucoside-	Pyridine alkaloids	CE000594
M34	444.43	Bufotalin (Saponin)	Saponin	TY000016
M35	124.12	Orcinol	Flavonoids	BML81850
M36	151.15	Cathine	Phenylpropanes	EQ333501
M37	165.14	D-Quercitol	Flavonoids	PubChem CID: 441437
M38	177.09	Ascorbic acid	Vitamin	PubChem CID: 54670067
M39	207.16	Anthraquinone		PubChem CID: 6780
M40	251.16	7-Hydroxy-3-methylflavone	Flavonoids	BML80610
M41	274.31	Phloretin	Dihydrochalchone (Phenol class)	TY000158
M42	301.18	Quercetin	Flavonoids	CE000168
M43	335.25	Senecionine	Pyrrolidizine alkaloids	FIO00235
M44	351.25	4-Methylumbelliferylglucuronide	Benzopyran alkaloids	CE000020
M45	353.26	Chelidonine	Phenylisoquinoline alkaloids	CE000133
M46	353.3	Asarinin	Benzofuran type lignan	BML80780
M47	413.28	Stigmasterol	Benzofuran type lignan	PubChem CID: 5280794
M48	429.4	Ononin	Isoflavonoid	PR020043
M49	523.39	1-Stearoylglycerophosphocholine	Glycerophospholipids	MT000126
M50	549.44	Quercetin-3-(6′′-malonyl)-glucoside	Flavonoid	PR101032
M51	579.45	Naringin	Flavonoid	CE000186
M52	593.3	Kaempferol-3-O-β-glucopyranosyl-7-O-α-rhamnopyranoside	Glycerophospholipids	PR101010
M53	639.34	Demethoxycentaureidin 7-O-rutinoside	Flavonoids	BML81075
M54	682.4	Deacyl gymnemic acid II	Triterpenoidal saponins	PubChem CID: 44144284
M55	693.52	Rutin 3′′-malonate	Flavonoids	PubChem CID: 10556617
M56	763.56	Gymnemic acid IV	Triterpenoidal saponins	PubChem CID: 14264063
M57	835.59	Triacylglycerol 16:0-16:0-18:0	Unsaturated fatty acids	UT000540
M58	877.51	Triacylglycerol 18:2-18:2-18:2	Unsaturated fatty acids	UT000521