Determination of Electroacupuncture Effects on circRNAs in Plasma Exosomes in Diabetic Mice: An RNA-Sequencing Approach

Table 7

The top 10 pathway enrichment of downregulated differentially expressed host linear transcripts affected by EA intervention.

Pathway	Selection counts		False discovery rate	Differentially expressed genes
Fc gamma R-mediated phagocytosis	5	<0.05	<0.05	PIP5K1B, PLCG2, PRKCA, RPS6KB1, CIN
HIF-1 signaling pathway	5	<0.05	<0.05	NFKB1, PDK1, PLCG2, PRKCA, RPS6KB1
Phosphatidylinositol signaling system	4	<0.05	<0.05	INPP4B, PIP5K1B, PLCG2, PRKCA
Choline metabolism in cancer	4	<0.05	<0.05	PIP5K1B, PRKCA, RPS6KB1, TSC2
Lysine degradation	3	<0.05	<0.05	EHMT1, NSD1, WHSC1
NOD-like receptor signaling pathway	3	<0.05	<0.05	ERBB2IP, MAP3K7, NFKB1
Thyroid hormone signaling pathway	4	<0.05	<0.05	MED12L, PLCG2, PRKCA, TSC2
mTOR signaling pathway	3	<0.05	<0.05	PRKCA, RPS6KB1, TSC2
Inositol phosphate metabolism	3	<0.05	<0.05	INPP4B, PIP5K1B, PLCG2
Proteoglycans in cancer	5	<0.05	<0.05	CTTN, KB1