Research Article

Evaluation of Male Fertility-Enhancing Activities of Water Seed Extract of Hunteria umbellata in Wistar Rats

Table 4

Effect of repeated daily oral treatments with 100-400 mg/kg/day of Hunteria umbellata aqueous seed extract on serum testosterone (TS), luteinizing hormone LH), follicle stimulating hormone (FSH), prolactin (PRL), and estradiol (ES) of treated rats.

GroupsTS (ng/ml)LH (ng/ml)FSH (ng/ml)PRL (ng/ml)ES (ng/ml)

I02.53 ± 0.040.66 ± 0.0302.32 ± 0.0403.14 ± 0.192.40 ± 0.06
II05.87 ± 0.601.47 ± 0.403.06 ± 0.002.86 ± 0.112.13 ± 0.07
III04.04 ± 0.100.83 ± 0.002.66 ± 0.002.82 ± 0.102.37 ± 0.04
IV04.70 ± 0.101.16 ± 0.002.76 ± 0.002.42 ± 0.172.46 ± 0.10
V06.39 ± 0.301.42 ± 0.003.25 ± 0.102.32 ± 0.02.41 ± 0.13
VI02.59 ± 0.0300.64 ± 0.0202.29 ± 0.0302.90 ± 0.302.28 ± 0.04

and represent significant increases at p<0.05, p<0.01, and p<0.001, respectively, when compared to Group I values, while represents a significant decrease at p<0.05 when compared to Group I values.
I = 10 ml/kg/day of distilled water.
II = 0.3 mg/kg/day of clomiphene dissolved in distilled water.
III = 100 mg/kg/day of Hunteria umbellata aqueous seed extract dissolved in distilled water.
IV = 200 mg/kg/day of Hunteria umbellata aqueous seed extract dissolved in distilled water.
V = 400 mg/kg/day of Hunteria umbellata aqueous seed extract dissolved in distilled water.
VI = 20 mg/kg/day of Vitamin C dissolved in distilled water.