Research Article

Network Pharmacology Deciphering Mechanisms of Volatiles of Wendan Granule for the Treatment of Alzheimer’s Disease

Table 2

Information of candidate targets, their corresponding gene symbols, and their degrees of correlation with compounds.

TargetGene symbolDegree

Gamma-aminobutyric acid receptor subunit alpha-1GABRA110

Prostaglandin G/H synthase 2PTGS210

Sodium-dependent noradrenaline transporterSLC6A210

Muscarinic acetylcholine receptor M1CHRM19

Alpha-1B adrenergic receptorADRA1B8

Muscarinic acetylcholine receptor M2CHRM28

Muscarinic acetylcholine receptor M3CHRM38

Alpha-1A adrenergic receptorADRA1A7

Beta-1 adrenergic receptorADRB17

Beta-2 adrenergic receptorADRB27

Prostaglandin G/H synthase 1PTGS17

Sodium-dependent dopamine transporterSLC6A37

Alpha-2A adrenergic receptorADRA2A6

Alpha-2C adrenergic receptorADRA2c6

cAMP-dependent protein kinase inhibitor alphaPKIA6

Gamma-aminobutyric-acid receptor alpha-2 subunitGABRA26

Alpha-2B adrenergic receptorADRA2B5

Gamma-aminobutyric-acid receptor subunit alpha-6GABRA65

Sodium channel protein type 5 subunit alphaSCN5A5

Sodium-dependent serotonin transporterSLC6A45

5-hydroxytryptamine 2A receptorHTR2A4

Alpha-1D adrenergic receptorADRA1D4

CGMP-inhibited 3′,5′-cyclic phosphodiesterase APDE3A4

Dopamine D1 receptorDRD14

Leukotriene A-4 hydrolaseLTA4H4

Amine oxidase [flavin-containing] AMAOA3

Amine oxidase [flavin-containing] BMAOB3

Gamma-aminobutyric-acid receptor alpha-3 subunitGABRA33

Glutamate receptor 2GRIA23

Retinoic acid receptor RXR-alphaRXRA3