Evidence-Based Complementary and Alternative Medicine

Research Article

In Vitro Schistosomicidal Activity of the Alkaloid-Rich Fraction from Ruta graveolens L. (Rutaceae) and Its Characterization by UPLC-QTOF-MS

Table 2

Chemical characterization of Rg-FAE by UPLC-ESI-QTOF-MS.


Peak	Proposed compounds	RT (min)	m/z experimental [M+H]⁺	Main fragments via MS/MS	Molecular formula	References

1	4-hydroxy-2-decylquinoline	3.72	286.0753	198.0591, 188.0791, 184.0822, 172. 0781, 132.0473	C₁₉H₂₇NO	[25]
2	4-hydroxy-2-undecylquinoline	4.66	300.0867	198.0937, 188.0735, 184.0739, 172.0781	C₂₀H₂₉NO	[25]
3	Graveoline	4.81	280.0962	265.0717, 237.0768, 207.0654	C₁₇H₁₃NO₃	[26, 27]
4	Graveolinine	5.36	280.0962	265.0717, 250.0862, 222.0900	C₁₇H₁₃NO₃	[26, 27]
5	Skimmianine	5.72	260.0886	245.0661, 230.0430, 216.0645, 199.0618	C₁₄H₁₃NO₄	[28, 29]
6	Arborinine	6.70	286.1064	271.0844, 253.0732, 244.1687, 225.0770, 197.0848, 182.0599	C₁₆H₁₅NO₄	[27]
7	Chalepin	7.93	315.1586	273.1148, 259.1003, 255.1037, 241.0889, 223.0753, 213.0933, 201.0573	C₁₉H₂₂O₄	[30]
8	1-methyl-2-nonyl-4(1H)-quinolone	8.77	286.2171	186.0907, 173.0827	C₁₉H₂₇NO	[31]
9	1-methyl-2-decyl-4(1H)-quinolone	9.23	300.2355	186.0907, 173.0827	C₂₀H₂₉NO	[31]
10	1-methyl-2-undecyl-4(1H)-quinolone	10.04	314.2481	186.0907, 173.0827	C₂₁H₃₁NO	[31]
11	1-methyl-2-dodecyl-4(1H)-quinolone	10.46	328.2617	186.0907, 173.0827	C₂₂H₃₃NO	[31]
12	Dihydroevocarpine	11.23	342.2783	186.0907, 173.0827	C₂₃H₃₅NO	[31]