The Mechanism of MAPK Signal Transduction Pathway Involved with Electroacupuncture Treatment for Different Diseases

Table 1

List of electroacupuncture treatment-related diseases based on MAPK signal pathway.

Effect	MAPK signal pathway	Number of articles	Summary
Analgesia	p38MAPK, ERK	19	The mechanism of anti-inflammatory effects and amelioration of neuropathic pain is more complete, while that of the curative effect is specific. There are few reports on anti-delivery pain, and the specific mechanism needs to be further clarified.
Resisting injury accelerates injury repair	p38MAPK, ERK	3	Few studies have reported advantages in acute lung injury and post-traumatic immunosuppression.
Regulate gastrointestinal functions	ERK	3	Few studies have reported the advantages of gastric mucosa repair and maintenance of gastrointestinal functions.
Intervention in cardiovascular and cerebrovascular diseases	p38MAPK, ERK, JNK	19	It has effective regulatory effects on cerebral ischemia-reperfusion, Alzheimer's disease, cardiomyopathy, Parkinson's disease, and hypertension.
Other effects	p38MAPK	3	Few studies have reported the advantages of electroacupuncture in allergic dermatitis and knee diseases.