Effects of Modulation of Ion Channel Currents by Salidroside in H9C2 Myocardial Cells in Hypoxia and Reoxygenation
Table 1
Boltzmann fitting parameters of and activation and inactivation curves in different groups.
Boltzmann fitting parameters
control #1
control #2
50mg/l
100mg/l
activation curves
(mV)
-17.48 ± 6.98
-20.27 ± 1.63
-17.80 ± 4.35
-15.94 ± 4.49
k
14.31 ± 4.29
9.02 ± 1.24
9.93 ± 2.94
14.22 ± 2.58
inactivation curves
(mV)
-40.40 ± 2.18
-44.69 ± 3.85
-44.67 ± 3.38
-46.14 ± 1.23
k
10.71 ± 2.11
14.23 ± 4.08
13.98 ± 3.55
5.49 ± 1.05
activation curves
(mV)
33.23 ± 8.94
19.59 ± 6.58
11.71 ± 3.53
4.49 ± 2.95
k
38.39 ± 5.32
25.72 ± 4.99
25.01 ± 3.48
21.59 ± 3.41
inactivation curves
(mV)
-60.81 ± 4.81
-65.50 ± 3.32
-65.12 ± 4.40
-57.01 ± 2.47
k
23.08 ± 3.87
15.89 ± 2.22
17.56 ± 2.96
15.75 ± 2.14
Boltzmann equation, G/Gmax= 1/ + exp[-(V-V1/2)/.where G is conductance, V is membrane potential, V1/2 is membrane potential at half-activation, and k is the slope factor. I/Imax = 1/ + exp[-(V-V1/2)/, where V is pre-pulse potential, V1/2 is membrane potential at half-activation, and k is the slope factor.
