Antidiabetic and Antihyperlipidemic Activities of the Leaf Latex Extract of Aloe megalacantha Baker (Aloaceae) in Streptozotocin-Induced Diabetic Model

Table 1

Effect of leaf latex extract of Aloe megalacantha on BGL of normoglycemic mice.

Group	Blood glucose (mg/dl) level in different time intervals (hours)
	0 h	1 h	2 h	3 h	4 h
DW 10	121.00 ± 1.93	120.33 ± 4.42	118.83 ± 6.50	123.50 ± 8.84	124.33 ± 10.05
GL5	114.50 ± 3.84	70.50 ± 3.41	62.00 ± 3.11	54.67 ± 2.74	48.67 ± 2.82
AM100	119.33 ± 2.11	103.17 ± 8.06	76.95 ± 5.18	72.00 ± 5.16	68.83 ± 7.68
AM200	110.67 ± 3.33	90.00 ± 10.48	84.83 ± 9.02	77.33 ± 10.93	68.67 ± 9.73
AM400	114.83 ± 3.60	85.28 ± 12.72	71.95 ± 9.71	66.67 ± 7.50	66.72 ± 8.75

Results are expressed in mean ± S.E.M, n = 6, DW10 = distilled water 10 ml/kg; GL5 = glibenclamide 5mg/kg; AM100 = A. megalacantha extract 100 mg/kg; AM200 = A. megalacantha extract 200mg/kg; AM400 = A. megalacantha extract 400mg/kg; compared with negative control group; compared with fasting blood glucose level; c compared with glibenclamide 5mg/kg (t = 0 h); ¹p < 0.05, ²p < 0.01, ³p < 0.001.