Research Article

Antidiabetic and Antihyperlipidemic Activities of the Leaf Latex Extract of Aloe megalacantha Baker (Aloaceae) in Streptozotocin-Induced Diabetic Model

Table 2

The effects of the leaf latex of Aloe megalacantha on postprandial glycemia in nondiabetic mice.

GroupBlood glucose level(mg/dl)
0 min 30 min 60 min 120 min 180 min

DW10103.67 ± 3.49183.33 ± 9.16155.17 ± 6.91109.00 ± 3.76101.83 ± 3.60
GL596.67 ± 1.89123.56 ± 10.877.50 ± 1.6867.67 ± 2.4361.67 ± 2.44
AM10099.33 ± 3.79135.67 ± 15.9874.17 ± 7.5561.76 ± 8.4569.78 ± 7.69
AM200101.17 ± 2.99161.83 ± 13.9362.17 ± 9.2955.95 ± 7.3562.00 ± 4.29
AM400100.00 ± 2.74171.17 ± 11.0883.83 ± 6.9975.61 ± 10.4071.00 ± 4.21

Results are expressed in mean ± S.E.M, n = 6, DW10 = distilled water 10 ml/kg, GL5 = glibenclamide 5mg/kg, AM100 = A. megalacantha extract 100 mg/kg, AM200 = A. megalacantha extract 200mg/kg, AM400 = A. megalacantha extract 400mg/kg, compared with negative control group, b compared with BGL at 0 min, c compared with BGL after 30 min, compared with glibenclamide 5mg/kg 1p < 0.05, 2p < 0.01,3p < 0.001