Research Article

Antidiabetic and Antihyperlipidemic Activities of the Leaf Latex Extract of Aloe megalacantha Baker (Aloaceae) in Streptozotocin-Induced Diabetic Model

Table 3

The effects of the leaf latex extract of Aloe megalacantha in STZ-induced diabetic mice.

GroupsBlood glucose level in mg/dL
Day 0Day 7Day 14

NC101.33 ± 4.0799.83 ± 3.20102.33 ± 3.88
DC264.33 ± 5.49266.83 ± 1.13268.83 ± 5.05
GL5256.33 ± 4.63219.50 ± 4.28191.67 ± 1.58
AM100265.33 ± 7.67241.50 ± 6.55203.83 ± 2.35
AM200262.17 ± 5.29239.50 ± 7.10204.00 ± 1.96
AM400265.50 ± 9.86241.17 ± 6.94202.00 ± 1.88

Results are expressed in mean ± S.E.M, n = 6; DW10 = distilled water 10 ml/kg; DC = diabetic control; GL5 = glibenclamide 5 mg/kg; AM100 = A. megalacantha extract 100 mg/kg; AM200 = A. megalacantha extract 200 mg/kg; AM400 = A. megalacantha extract 400 mg/kg; compared with diabetic control group, compared to 0 days, compared to 7 days, 1p < 0.05, 2p < 0.01, 3p < 0.001.