Therapeutic Effects of Chinese Herbal Formula (PTQX) on NC/Nga Mice with Atopic Dermatitis-Like Skin Lesions

Figure 5

PTQX suppresses tissue inflammation and immune cell infiltration in NC/Nga mice. Atopic dermatitis was induced by the repeated topical application of 1-chloro-2,4-dinitrobenzene (DNCB), with or without PTQX treatment. Sections of the ears (a) and dorsal skin (b) were stained with haematoxylin and eosin (HE). The ear tissues were also subjected to an immunohistochemical analysis of CD4+ (c) and CD8+ (d) T lymphocytes to estimate epidermal inflammation (arrows). A representative example of 3 independent experiments is shown.

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