C-Phycocyanin Alleviates Bladder Inflammation and Dysfunction in Cyclophosphamide-Induced Cystitis in a Mouse Model by Inhibiting COX-2 and EP4

<p><i>The expressions of TRPV1 and EP4 in bladder</i>. EP4 (red) and TRPV1 (green) innervation in lower urinary bladder. EP4-IR and TRPV1-IR signals were weak in the control group. EP4-IR was primarily localized to the detrusor muscle, and TRPV1-IR primarily passed through the suburothelium and smooth muscle cells following CYP treatment. Yellow dotted lines delineated the boundary of the urothelium. Scale bar 50 <i>μ</i>m in the panels.</p>

Evidence-Based Complementary and Alternative Medicine

fig5

Figure 5

Figure 5: C-Phycocyanin Alleviates Bladder Inflammation and Dysfunction in Cyclophosphamide-Induced Cystitis in a Mouse Model by Inhibiting COX-2 and EP4 

Figure 5 | C-Phycocyanin Alleviates Bladder Inflammation and Dysfunction in Cyclophosphamide-Induced Cystitis in a Mouse Model by Inhibiting COX-2 and EP4 