Evidence-Based Complementary and Alternative Medicine / 2019 / Article / Fig 5

Research Article

C-Phycocyanin Alleviates Bladder Inflammation and Dysfunction in Cyclophosphamide-Induced Cystitis in a Mouse Model by Inhibiting COX-2 and EP4

Figure 5

The expressions of TRPV1 and EP4 in bladder. EP4 (red) and TRPV1 (green) innervation in lower urinary bladder. EP4-IR and TRPV1-IR signals were weak in the control group. EP4-IR was primarily localized to the detrusor muscle, and TRPV1-IR primarily passed through the suburothelium and smooth muscle cells following CYP treatment. Yellow dotted lines delineated the boundary of the urothelium. Scale bar 50 μm in the panels.

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