Research Article

Effect of Xylocarpus granatum Bark Extract on Amelioration of Hyperglycaemia and Oxidative Stress Associated Complications in STZ-Induced Diabetic Mice

Table 4

Effect of X. granatum on serum biochemical parameters in STZ-induced diabetic mice. Data are expressed as mean ± SD, n=5. NC, Control mice; NCT, Normal Control mice +Toxicological (high) dose Xylocarpus granatum; DMC, Diabetic Control mice; DMD, Diabetic mice+ Drug (Glibenclamide); DML, Diabetic mice + Xylocarpus granatum Low dose (100 mg/kg); DMH, Diabetic mice + Xylocarpus granatum High dose (200 mg/kg). p< 0.05 compared with the control mice (NC); p< 0.05 compared with the diabetic control mice (DMC).

GroupsTG (mg/dL)TC (mg/dL)SGOT (U/L)SGPT (U/L)Urea(mg/dL)

NC138.8 ± 5.89102.6 ± 6.91197.6 ± 13.8489.6 ± 7.327 ± 1.58
NCT152.6 ± 7.0687.8 ± 15.23261 ± 19.72116.8 ± 8.9530.0 ± 1.0
DMC261.4 ± 11.43194.8 ± 12.3326.0 ± 9.38181.8 ± 8.0141.6 ± 2.60
DMD177.6 ± 6.23110.0 ± 17.42209.4 ± 25.48130.2 ± 5.2127.4 ± 2.07
DML219.4 ± 16.26131.6 ± 8.32242.6 ± 14.53152.4 ± 6.8435.2 ± 2.04
DMH187.2 ± 10.06104.6 ± 12.93198.6 ± 9.60118.6 ± 19.0928.4 ± 1.51