Effect of Xylocarpus granatum Bark Extract on Amelioration of Hyperglycaemia and Oxidative Stress Associated Complications in STZ-Induced Diabetic Mice

Table 5

Effect of X. granatum on lipid peroxidation (LPx), non-protein-SH (NP-SH) and protein-SH (P-SH) in liver and brain tissues. Data are expressed as mean ± S.D. (n=5). NC, Control mice; NCT, Normal Control mice +Toxicological (high) dose Xylocarpus granatum; DMC, Diabetic Control mice; DMD, Diabetic mice+ Drug (Glibenclamide); DML, Diabetic mice + Xylocarpus granatum Low dose (100 mg/kg); DMH, Diabetic mice + Xylocarpus granatum High dose (200 mg/kg). p< 0.05 compared with the control mice (NC); p< 0.05 compared with the diabetic control mice (DMC).

Organs	Group	LPx	NP-SH	P-SH
		(nmolesTBARS/mg)	(μM/g tissue)	(μM/g tissue)
Liver	NC	0.60 ± 0.07	2.07 ± 0.28	4.91 ± 0.38
	NCT	0.54 ± 0.13	2.17 ± 0.20	4.38 ± 0.23
	DMC	0.75 ± 0.02	2.18 ± 0.22	4.07 ± 0.23
	DMD	0.77 ± 0.11	1.67 ± 0.37	2.99 ± 0.15
	DML	0.72 ± 0.19	1.81 ± 0.40	2.22 ± 0.33
	DMH	0.73 ± 0.12	1.24 ± 0.19	2.96 ± 0.48
Brain	NC	1.68 ± 0.24	0.60 ± 0.07	4.34 ± 0.29
	NCT	0.66 ± 0.09	0.56 ± 0.03	4.05 ± 0.21
	DMC	1.58 ± 0.27	0.61± 0.04	4.31 ± 0.43
	DMD	0.60 ±0.1	0.59 ± 0.03	4.59 ± 0.29
	DML	1.22 ± 0.18	0.55± 0.11	4.47 ± 0.20
	DMH	0.81 ± 0.17	0.76 ± 0.07	4.46± 0.77