iTRAQ-Based Proteomics Analysis of Plasma of Myasthenia Gravis Patients Treated with Jia Wei Bu Zhong Yi Qi Decoction

Table 4

Interacted proteins with combined score ≥0.9.

Node1	Node2	Homology	Coexpression	Experimentally_determined_interaction	Database_annotated	Automated_textmining	Combined_score
MYL6	MYH9	0	0.64	0.858	0.9	0.711	0.998
APOA2	APOC3	0	0.796	0	0.9	0.86	0.996
TUBB	TUBA1A	0.92	0.227	0.948	0.9	0.591	0.995
AHSG	APOA2	0	0.918	0	0.9	0.455	0.995
APOA5	APOC3	0	0.466	0	0.9	0.86	0.991
TUBB	TUBA4A	0.92	0.189	0.881	0.9	0.679	0.99
APOA4	APOC3	0	0.565	0	0.9	0.789	0.99
AHSG	ITIH2	0	0.841	0	0.9	0.439	0.99
AHSG	HRG	0	0.67	0	0.9	0.644	0.987
AHSG	TF	0	0.68	0	0.9	0.571	0.985
AHSG	IGFBP1	0	0.788	0	0.9	0.25	0.982
TF	APOA2	0	0.675	0	0.9	0.502	0.982
TUBA1A	TUBA4A	0.986	0	0.809	0.9	0.58	0.98
CD14	LBP	0	0.063	0.379	0.9	0.712	0.98
ILK	RSU1	0	0.265	0.925	0	0.674	0.98
PF4	PPBP	0.886	0.786	0	0.9	0.922	0.98
VWF	THBS1	0	0.063	0	0.9	0.785	0.978
C1R	C4A	0	0.183	0.05	0.9	0.746	0.977
AHSG	PROC	0	0.742	0	0.9	0.128	0.975
APOA2	ITIH2	0	0.728	0	0.9	0.128	0.974
THBS1	HRG	0	0	0.379	0.9	0.609	0.973
SERPINA5	PROC	0	0.177	0.435	0.9	0.416	0.969
APOA5	APOA2	0	0.399	0	0.9	0.526	0.969
C1R	C1QC	0	0.119	0	0.9	0.666	0.968
PF4	VWF	0	0.061	0	0.9	0.685	0.967
TF	ITIH2	0	0.578	0	0.9	0.297	0.967
HIST1H4A	HIST3H3	0	0.107	0.494	0.9	0.371	0.967
TF	CP	0	0.181	0	0.9	0.636	0.967
PPBP	VWF	0	0.061	0	0.9	0.669	0.966
MYL6	TPM4	0	0.185	0.185	0.9	0.546	0.965
APOA2	IGFBP1	0	0.645	0	0.9	0.101	0.965
ACTN1	TLN1	0	0.116	0.083	0.9	0.622	0.965
APOA2	APOA4	0	0.115	0	0.9	0.626	0.964
AHSG	CP	0	0.157	0	0.9	0.609	0.964
ILK	HSP90AA1	0	0	0.161	0.9	0.584	0.962
C8A	C9	0.781	0.341	0.379	0.9	0.576	0.96
APOA5	AHSG	0	0.556	0	0.9	0.189	0.96
C4A	C1QC	0	0.16	0	0.9	0.551	0.959
ITIH2	PROC	0	0.593	0	0.9	0.05	0.957
C4A	APOA2	0	0.083	0.379	0.9	0.308	0.955
PF4	THBS1	0	0.06	0	0.9	0.561	0.955
ITIH2	IGFBP1	0	0.554	0	0.9	0	0.953
ADIPOQ	CRP	0	0	0	0	0.952	0.952
TUBB	HSP90AA1	0	0.129	0.13	0.9	0.411	0.949
HSP90AA1	TUBA1A	0	0.062	0.305	0.9	0.305	0.948
APOA2	PON1	0	0.141	0	0.72	0.794	0.946
APOA2	CP	0	0.115	0	0.9	0.44	0.946
MYL6	TLN1	0	0.427	0	0.9	0.135	0.946
APOA5	TF	0	0.175	0	0.9	0.406	0.946
C4A	TF	0	0.159	0	0.9	0.405	0.945
PF4	HRG	0	0	0	0.9	0.471	0.944
ILK	ACTN1	0	0.064	0.133	0.9	0.38	0.943
PF4	PROC	0	0	0.379	0.9	0.164	0.943
TF	IGFBP1	0	0.214	0.313	0.9	0.073	0.943
CP	PROC	0	0.111	0.379	0.9	0.09	0.943
PLTP	APOA2	0	0	0.379	0.72	0.7	0.943
APOA5	IGFBP1	0	0.394	0	0.9	0.126	0.942
ITIH2	CP	0	0.24	0	0.9	0.289	0.941
APOA5	ITIH2	0	0.428	0	0.9	0	0.94
C4A	CP	0	0.159	0	0.9	0.35	0.94
FLNA	VWF	0	0.061	0.085	0.9	0.38	0.939
ITIH2	FETUB	0	0.916	0	0	0.31	0.939
C1R	CRP	0	0.061	0	0.9	0.399	0.938
APOC3	CETP	0	0.06	0	0.72	0.785	0.938
APOA5	C4A	0	0.106	0	0.9	0.363	0.938
C4A	AHSG	0	0.148	0	0.9	0.322	0.937
APOA5	APOA4	0.681	0.197	0	0.9	0.802	0.937
IGFBP3	IGFBP1	0.755	0.214	0	0.9	0.929	0.936
VWF	PROC	0	0	0	0.9	0.392	0.936
PPBP	THBS1	0	0.062	0	0.9	0.363	0.935
EFEMP1	FBLN1	0.72	0.16	0.12	0.9	0.709	0.935
TF	IGFBP3	0	0.096	0.313	0.9	0.057	0.933
HSP90AA1	TUBA4A	0	0.055	0	0.9	0.342	0.932
C4A	ITIH2	0	0.177	0	0.9	0.237	0.931
APOA5	PROC	0	0.338	0	0.9	0	0.931
SERPINA5	VWF	0	0	0	0.9	0.31	0.928
C4A	PROC	0	0.128	0.05	0.9	0.231	0.927
VWF	HRG	0	0.06	0	0.9	0.292	0.927
TLN1	VWF	0	0.055	0	0.9	0.282	0.926
APOA2	PROC	0	0.275	0	0.9	0.062	0.926
IGFBP1	PROC	0	0.287	0	0.9	0	0.925
AHSG	IGFBP3	0	0.152	0	0.9	0.197	0.925
TPM4	TLN1	0	0.089	0	0.9	0.247	0.925
APOA5	CETP	0	0.061	0	0.72	0.735	0.924
APOA2	CETP	0	0	0	0.72	0.738	0.923
IGFBP1	CP	0	0.146	0	0.9	0.164	0.922
C4A	C8A	0	0.127	0	0	0.914	0.922
PPBP	HRG	0	0	0	0.9	0.25	0.921
ITIH3	ITIH4	0.896	0.18	0	0.9	0.718	0.92
ACTN1	THBS1	0	0.098	0	0.9	0.186	0.92
C1QC	CRP	0	0	0	0.9	0.236	0.92
SAA1	PF4	0	0.061	0	0.9	0.195	0.917
SAA1	PPBP	0	0.063	0	0.9	0.195	0.917
ACTN1	VWF	0	0.061	0.17	0.9	0.066	0.917
IGFBP3	APOA2	0	0.141	0	0.9	0.107	0.916
AHSG	THBS1	0	0	0	0.9	0.189	0.915
TF	HSP90B1	0	0	0	0.9	0.168	0.913
TF	PROC	0	0.147	0.067	0.9	0	0.913
C4A	IGFBP1	0	0.116	0	0.9	0.096	0.913
PON1	CETP	0	0	0	0.72	0.703	0.913
AHSG	PF4	0	0	0	0.9	0.161	0.912
AHSG	VWF	0	0.057	0	0.9	0.144	0.912
APOA5	CP	0	0.116	0	0.9	0.071	0.91
APOA2	HSP90B1	0	0	0	0.9	0.135	0.909
IGFBP3	ITIH2	0	0.112	0	0.9	0	0.907
C4A	IGFBP3	0	0.095	0	0.9	0.061	0.907
AHSG	PPBP	0	0	0	0.9	0.111	0.907
HSP90B1	CP	0	0.077	0	0.9	0.08	0.907
IGFBP3	CP	0	0.076	0	0.9	0.076	0.907
ACTN1	PF4	0	0	0	0.9	0.116	0.907
ACTN1	PPBP	0	0	0	0.9	0.111	0.907
ITIH2	HSP90B1	0	0	0	0.9	0.104	0.906
IGFBP3	HSP90B1	0	0	0	0.9	0.093	0.905
APOA5	IGFBP3	0	0.069	0	0.9	0.061	0.904
AHSG	HSP90B1	0	0	0	0.9	0.072	0.903
C4A	HSP90B1	0	0.061	0	0.9	0.042	0.902
IGFBP3	PROC	0	0.062	0	0.9	0	0.902
AHSG	ACTN1	0	0	0	0.9	0.058	0.901
HSP90B1	IGFBP1	0	0	0	0.9	0.058	0.901
HSP90B1	PROC	0	0	0	0.9	0	0.9
APOA5	HSP90B1	0	0	0	0.9	0	0.9
ACTN1	HRG	0	0	0	0.9	0	0.9