Xiaokeping Mixture Attenuates Diabetic Kidney Disease by Modulating TGF-β/Smad Pathway in db/db Mice

Figure 1

Effects of xiaokeping mixture on biochemical indicators. Mice in the model exhibited significantly increased level of blood glucose, and XKP has some effect on the regulation of blood glucose levels (a). XKP can prevent the elevation of blood urea nitrogen while it increases in the model group (b). Serum creatinine (c) and urine creatinine (d) both also increase in the model group, which reduced significantly by treatment of XKP. The same is true for the effect of XKP on urine albumin (e). Data presented are means ± SD. Compared with control, ^▲p < 0.05, ^▲▲p < 0.01. Compared with model, ^∗p < 0.05, ^∗∗p < 0.01.

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