Randomized, Double-Blinded, Multicenter, Placebo-Controlled Trial of Shenfu Injection for Treatment of Patients with Chronic Heart Failure during the Acute Phase of Symptom Aggravation (Yang and Qi Deficiency Syndrome)

<table class="fixed-width table-group" id="tab9"><tr class="table-caption" id="a"><td><div><b>(a) </b>Comparison of ADRs (top 10) between SFI and placebo groups</div></td></tr><tr><td><table class="table"><colgroup><col style="width:4.37em"/><col style="width:5.60em"/><col style="width:7.42em"/><col style="width:5.80em"/></colgroup><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr class="thead"><td class="align_left">ADR</td><td class="align_center">SFI (n=78)</td><td class="align_center">Placebo (n=79)</td><td class="align_center">All (n=157)</td></tr><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr><td class="align_left">Chills</td><td class="align_center">1 (1.28%)</td><td class="align_center">0 (0.00%)</td><td class="align_center">1 (0.64%)</td></tr><tr><td class="align_left">Erythra</td><td class="align_center">1 (1.28%)</td><td class="align_center">0 (0.00%)</td><td class="align_center">1 (0.64%)</td></tr><tr><td class="align_left">Total</td><td class="align_center">2 (2.56%)</td><td class="align_center">0 (0.00%)</td><td class="align_center">2 (1.27%)</td></tr><tr class="table-tr"><td colspan="4"><hr class="tbody-hr"/></td></tr></table></td></tr><tr class="table-caption" id="b"><td><div><b>(b) </b>Accessory: list of ADRs</div></td></tr><tr><td><table class="table"><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr class="thead"><td class="align_left">Subject number</td><td class="align_center">Group</td><td class="align_center">ADR symptom</td><td class="align_center">ADR description</td></tr><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr><td class="align_left">006002</td><td class="align_center">SFI</td><td class="align_center">Chill</td><td class="align_center">Chill occurred after injection of 10 ml SFI.</td></tr><tr><td class="align_left">010070</td><td class="align_center">SFI</td><td class="align_center">Erythra</td><td class="align_center">The subject felt itchy skin after 1 day of medication. Skin flushing was seen on the upper parts of the chest and abdomen, the medial buttocks, and both lower limbs. There was scratch, but no break.</td></tr><tr class="table-tr"><td colspan="4"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

Evidence-Based Complementary and Alternative Medicine

tab9

Table 9

Table 9: Randomized, Double-Blinded, Multicenter, Placebo-Controlled Trial of Shenfu Injection for Treatment of Patients with Chronic Heart Failure during the Acute Phase of Symptom Aggravation (Yang and Qi Deficiency Syndrome) 

Table 9 | Randomized, Double-Blinded, Multicenter, Placebo-Controlled Trial of Shenfu Injection for Treatment of Patients with Chronic Heart Failure during the Acute Phase of Symptom Aggravation (Yang and Qi Deficiency Syndrome) 