Effect of Tripterygium wilfordii Polycoride on the NOXs-ROS-NLRP3 Inflammasome Signaling Pathway in Mice with Ulcerative Colitis

Table 8

The mRNA expression of NLRP3, ASC, and caspase-1 in the colon tissues (2^−ΔΔCt) (mean ± SD, n = 9).

Group	NLRP3	ASC	Caspase-1
Model control group	1.01 ± 0.13	0.89 ± 0.10	0.81 ± 0.15
Low TWP group	0.60 ± 0.09	0.76 ± 0.10	0.32 ± 0.04
Middle TWP group	0.45 ± 0.06^†	0.50 ± 0.07^†	0.24 ± 0.02^†
High TWP group	0.31 ± 0.05^†^▶	0.35 ± 0.06^†^▶	0.16 ± 0.03^†^▶
Normal control group	0.17 ± 0.01	0.22 ± 0.02	0.09 ± 0.01

Note: vs. model; ^† vs. low TWP; ^▶ vs. middle TWP.