Comparative Pharmacokinetic Study of Taxifolin after Oral Administration of Fructus Polygoni Orientalis Extract in Normal and Fibrotic Rats by UPLC-MS/MS

Table 2

Liver function and serum liver fibrosis indexes after PS treatment for 12 weeks (n = 3).

Characterize	ALT (IU/L)	AST (IU/L)	HA (pg/mL)	LN (ng/mL)	IV-C (ng/mL)	PCIII (ng/mL)
Normal	37.10 ± 9.45	97.96 ± 11.33	247.09 ± 15.72	5.74 ± 1.58	34.76 ± 1.11	11.71 ± 0.84
Model	72.95 ± 21.10	173 ± 59.29	291.18 ± 40.44	13.56 ± 1.85	41.53 ± 1.53	17.45 ± 3.47
value	<0.05	<0.05	<0.01	<0.01	<0.01	<0.01