Phytopharmacovigilance in the Elderly: Highlights from the Brazilian Amazon
Table 2
Clinic characteristics regarding only medication and herbal medicines in combination with medication use reported by the elderly participants (N=208), Macapá, Brazil, 2016-2017.
Clinic Index
Only medications use n ()
Herbal medicines and medications use n ()
Total n ()
p value
Health problems
p = 0.004
Hypertension
58 (35.8)
64 (33.0)
122 (34.3)
Rheumatic diseases
29 (17.9)
44 (22.7)
73 (20.5)
Diabetes
19 (11.7)
28 (14.4)
47 (13.2)
Heart problems
12 (7.4)
8 (4.1)
20 (5.6)
Gastritis
4 (2.5)
12 (6.2)
16 (4.5)
Dyslipidemias
8 (5.0)
6 (3.1)
14 (3.9)
Depression
4 (2.5)
4 (2.1)
8 (2.25)
Labyrinthitis
2 (1.2)
6 (3.1)
8 (2.25)
Others
26 (17.2)
22 (11.3)
48 (13.5)
Total
162 (100)
194 (100)
356 (100)
Polypharmacy
p < 0.0001
Yes
10 (11.8)
36 (29.3)
46 (22.1)
No
75 (88.2)
87 (70.7)
162 (77.9)
Total
85 (100)
123 (100)
208 (100)
Adverse Drug Reaction (ADR) suspected
Yes
29 (34.1)
57 (46.3)
86 (41.3)
p = 0.045
No
56 (65.9)
66 (53.7)
122 (58.7)
Total
85 (100)
123 (100)
208 (100)
according to Kennerfalk et al. (2002) [23]. Polypharmacy: ≥5 medicines. Student T-test.
