Keratinocyte Growth Factor-2 Is Protective in Oleic Acid-Induced Acute Lung Injury in Rats
Figure 1
(a) Pathological changes of lung tissue in each group were observed under light microscope. (A) The alveolar structure of the control group was intact (middle magnification); (D) there was no obvious inflammatory cell infiltration in the control group and no significant change in the pulmonary interstitial (high magnification); (B) alveolar septal thickening in the ALI group, alveolar fusion (middle magnification); (E) inflammatory cells in the ALI group were extensively infiltrated and a large amount of protein exuded (high magnification); (C) mild fusion of alveolus in the ALI+KGF-2 group (middle magnification); (F) a small amount of inflammatory cell infiltration in ALI+KGF-2 group and a small amount of protein exudation (high magnification) HE staining. (b) Quantitative analysis of lung injury scores in each group ( 0.01 versus control group, #< 0.01 versus ALI group).