Research Article

Cytotoxic Effects of Chlorophyllides in Ethanol Crude Extracts from Plant Leaves

Table 2

IC50 and SI values of chlase-treated crude extracts from leaves on cancer cell line.

Plant speciesMCF7MDA-MB-231Hep G2Caco2U-118 MGNIH/3T3
IC50SIIC50SIIC50SIIC50SIIC50SIIC50

Guava>2001.03>2001.10>2000.72>2001.41133.552.37>200
Sweet potato122.290.6782.900.9963.731.2980.731.0243.171.91582.08
Lemon117.471.0695.751.31>2000.37105.771.1850.152.49125.01
Banana104.414.60186.992.57192.072.50N/A1.00119.594.02>200
Toona>2001.02107.242.12>2000.74154.631.47206.011.10>200
Longan>2000.72>2000.56>200N/A>2000.99>2001.28>200
Wax apple88.871.6397.831.48>2000.57>2000.6652.642.75144.90
Mango>200N/A>200N/A>200N/A>200N/A>200N/A>200
Caimito>200N/A>200N/A>200N/A>200N/A>200N/A>200
Cacao>200N/A>200N/A>200N/A>200N/A>200N/A>200

Data are presented as the mean ± standard deviation following 5 replicative experiments. IC50, half maximal inhibitory concentration (μg/ml); SI, selectivity index; N/A: not available.