Antimetastasis Effect of Astragalus membranaceus-Curcuma zedoaria via β-Catenin Mediated CXCR4 and EMT Signaling Pathway in HCT116

Figure 4

Overexpression of CXCR4 partly rescued the HCT116 cells from HQEZ. (a) Overexpression of CXCR4 rescued the metastasis ability of HCT116 cells. (b) Overexpression of CXCR4 partly rescued the EMT signal pathway and β-catenin. (c, d) In wild-type HCT116 and CXCR4 overexpressed HCT116, administration of HQEZ did not influence the mRNA level of β-catenin.

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