Safety and Efficacy of the C-117 Formula for Vulnerable Carotid Artery Plaques (Spchim): A Randomized Double-Blind Controlled Pilot Study

Table 1

Study inclusion and exclusion criteria.

Inclusion criteria
1	Meet the diagnostic criteria of carotid artery atherosclerosis
2	Ultrasound of carotid artery atherosclerotic plaque specifies it as an
	unstable plaque (including malakoplakia and mixed plaque);
3	Can persist on long-term medication
4	Older than 18 and under 80 years old
5	Meet the diagnostic criteria of hyperlipidaemia: Fasting serum total cholesterol ≥ 5.72 mmol/L or triglycerides ≥ 1.70 mmol/L or low density lipoprotein ≥ 1.8 mmol/L;
Exclusion Criteria:
1	mRS rating higher than or equal to 3 before joining the trial group;
2	Carotid artery stenosis higher than or equal to 50%;
3	Confirmed or suspected vasculitis;
4	Infection, tumour or insufficient heart, liver and kidney functions
	(renal function higher than twice the upper limit in normal limits,
	HYHA heart function grading higher than or equal to level 2);
5	Acute myocardial infarction and unstable angina pectoris;
6	Acute cerebral arterial thrombosis;
7	Severe stenosis or occlusion of distal intracranial vessels;
8	Pregnant women or lactating mothers;
9	Known history of allergy to the trial drugs.