Safety and Efficacy of the C-117 Formula for Vulnerable Carotid Artery Plaques (Spchim): A Randomized Double-Blind Controlled Pilot Study

Table 3

Plaque characteristics of the two groups.

	C-117 formula group (n=59)	Placebo group (n=59)	Z/T	P
Bilateral IMT (mm)
Before treatment	1.88 ± 0.44	1.89 ± 0.41
After treatment	1.78 ± 0.35	1.77 ± 0.33	-0.005	0.996
Crouse score (mm)
Before treatment	4.77 ± 3.06	3.96 ± 2.60
After treatment	3.96 ± 2.60	3.80 ± 2.91	-1.233	0.217
Plaque area (mm^2)
Before treatment	56.07 ± 71.15	38.13 ± 29.86
After treatment	53.92 ± 55.58	38.48 ± 46.60	-1.416	0.157
Number of vulnerable plaques (n)
Before treatment	2.12 ± 1.22	1.80 ± 0.92
After treatment	2.19 ± 1.27	1.93 ± 1.11	-0.960	0.337
Number of stable plaques (n)
Before treatment	0.33 ± 0.54	0.25 ± 0.60
After treatment	0.31 ± 0.56	0.24 ± 0.50	-0.673	0.501
Total number of plaques (n)
Before treatment	2.46 ± 1.30	2.05 ± 1.11
After treatment	2.49 ± 1.36	2.17 ± 1.25	-1.295	0.195

M, mean ± standard deviation. P is the P value of the FAS dataset;
P<0.05 vs. before treatment.