Research Article

Chinese Herbal Injections for Primary Nephrotic Syndrome in Adults: A Systematic Review and Network Meta-Analysis

Table 1

Network meta-analyses of complete remission and total remission.

Total remission

YXY + WM0.52 (0.05, 5.70)0.67 (0.06, 7.03)0.82 (0.08, 8.48)1.37 (0.13, 14.56)0.48 (0.04, 5.68)0.68 (0.06, 7.15)1.07 (0.10, 11.55)0.90 (0.09, 9.49)1.08 (0.09, 12.43)3.15 (0.31, 31.62)
0.89 (0.31, 2.60)SXT + WM1.29 (0.57, 2.92)1.59 (0.73, 3.45)2.65 (1.33, 5.28)0.94 (0.31, 2.81)1.31 (0.59, 2.91)2.08 (0.84, 5.10)1.75 (0.83, 3.70)2.10 (0.73, 6.01)6.12 (3.10, 12.08)
1.18 (0.44, 3.15)1.33 (0.65, 2.69)SK + WM1.23 (0.67, 2.28)2.05 (1.00, 4.22)0.72 (0.27, 1.95)1.02 (0.50, 2.05)1.61 (0.75, 3.47)1.36 (0.77, 2.39)1.63 (0.63, 4.17)4.74 (2.89, 7.77)
1.41 (0.55, 3.59)1.58 (0.83, 3.02)1.19 (0.73, 1.93)HQ + WM1.66 (0.86, 3.20)0.59 (0.23, 1.52)0.82 (0.44, 1.54)1.30 (0.65, 2.62)1.10 (0.62, 1.96)1.32 (0.54, 3.20)3.84 (2.64, 5.59)
1.80 (0.67, 4.81)2.02 (1.13, 3.61)1.52 (0.86, 2.70)1.28 (0.78, 2.09)FFDS + WM0.35 (0.13, 0.98)0.50 (0.27, 0.91)0.78 (0.35, 1.74)0.66 (0.34, 1.31)0.79 (0.30, 2.08)2.31 (1.35, 3.95)
1.27 (0.43, 3.74)1.42 (0.61, 3.30)1.07 (0.52, 2.21)0.90 (0.46, 1.75)0.70 (0.34, 1.46)DZH + WM1.40 (0.51, 3.84)2.22 (0.77, 6.37)1.88 (0.73, 4.82)2.24 (0.68, 7.36)6.54 (2.72, 15.71)
0.95 (0.36, 2.52)1.06 (0.54, 2.09)0.80 (0.45, 1.41)0.67 (0.41, 1.09)0.53 (0.32, 0.86)0.75 (0.36, 1.54)DH + WM1.58 (0.73, 3.42)1.34 (0.68, 2.61)1.60 (0.62, 4.12)4.66 (2.83, 7.68)
1.59 (0.57, 4.41)1.78 (0.83, 3.84)1.35 (0.71, 2.54)1.13 (0.65, 1.98)0.88 (0.47, 1.68)1.25 (0.58, 2.74)1.68 (0.89, 3.16)DSCX + WM0.85 (0.40, 1.78)1.01 (0.43, 2.37)2.95 (1.64, 5.31)
1.46 (0.56, 3.81)1.64 (0.86, 3.12)1.23 (0.76, 1.99)1.04 (0.68, 1.59)0.81 (0.48, 1.37)1.15 (0.59, 2.25)1.54 (0.91, 2.61)0.92 (0.50, 1.67)DS + WM1.20 (0.47, 3.02)3.49 (2.21, 5.51)
1.57 (0.53, 4.58)1.76 (0.76, 4.06)1.32 (0.64, 2.72)1.11 (0.58, 2.14)0.87 (0.42, 1.79)1.23 (0.53, 2.89)1.65 (0.81, 3.39)0.98 (0.50, 1.95)1.07 (0.54, 2.14)CXQ + WM2.92 (1.31, 6.51)
3.25 (1.33, 7.95)3.64 (2.02, 6.57)2.75 (1.84, 4.11)2.31 (1.76, 3.04)1.81 (1.20, 2.72)2.56 (1.40, 4.70)3.43 (2.30, 5.13)2.04 (1.25, 3.33)2.23 (1.57, 3.15)2.08 (1.14, 3.77)WM

Complete remission

The results of network meta-analyses are presented as odds ratios (95% confidence intervals) for complete remission (bottom left) and total remission (upper right). The risk estimate is for the column-defining treatment compared to the row-defining treatment. Statistical significance is defined as 95% confidence intervals that do not overlap 1.0. WM = Western medicine, YXY = Yinxingye injection, SXT = Shuxuetong injection, SK = Shenkang injection, HQ = Huangqi injection, FFDS = Fufangdanshen injection, DZH = Dengzhanhua injection, DH = Danhong injection, DSCX = Danshenchuanxiongqin injection, DS = Danshen injection, and CXQ = Chuanxiongqin injection.