Guanxinshutong Alleviates Atherosclerosis by Suppressing Oxidative Stress and Proinflammation in ApoE^−/− Mice

Figure 3

GXST reduces the lesion area and plaque composition, (a) representative images of oil red O-stained aortic trunk in each group (n = 3), (b) representative images of HE-stained aortic sinus sections from Sham, model, GXST, and atorvastatin (n = 5), (c) representative images of Masson-stained aortic sinus sections from Sham, model, GXST, and atorvastatin (n = 5), (d) representative photomicrographs images of aortic root sections stained with CD68 in each group (n = 3), (e) the size of the aortic trunk lesion was calculated as the percentage of lesion area in each group (n = 5), (f) quantitative analysis of the lesion size root in each group (n = 8), (g) quantitative analysis of the extracellular matrix in each group (n = 8), (h) quantitative analysis of CD68 in each group (n = 5). showed a significant difference compared with the Sham. showed a significant difference compared with the model, , , ; , , ).

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