Acute and 28-Day Repeated-Dose Oral Toxicity Assessment of Abelmoschus moschatus Medik. in Healthy Wistar Rats

Table 3

Relative weight of organs (g/g BW) after treatment with selected plant extracts of Abelmoschus moschatus for 28 days.

	Normal control	Vehicle corn oil	Vehicle PVP	Hexane extract	Ethyl acetate extract	Butanol extract	Aqueous extract
Heart	0.33 ± 0.01	0.33 ± 0.01	0.35 ± 0.01	0.32 ± 0.01	0.32 ± 0.00	0.32 ± 0.01	0.34 ± 0.01
Liver	2.68 ± 0.03	2.60 ± 0.04	2.61 ± 0.04	2.62 ± 0.05	2.57 ± 0.05	2.74 ± 0.04	2.71 ± 0.07
Small intestine	1.78 ± 0.09	1.43 ± 0.12	1.73 ± 0.12	1.51 ± 0.07	1.52 ± 0.15	1.48 ± 0.09	1.48 ± 0.09
Lungs	0.54 ± 0.01	0.47 ± 0.02^a	0.50 ± 0.02	0.51 ± 0.02	0.49 ± 0.00	0.49 ± 0.02	0.52 ± 0.01
Spleen	0.25 ± 0.00	0.24 ± 0.01	0.25 ± 0.01	0.24 ± 0.01	0.26 ± 0.01	0.24 ± 0.01	0.24 ± 0.01
Kidneys	0.59 ± 0.01	0.56 ± 0.01	0.55 ± 0.01	0.55 ± 0.01	0.52 ± 0.01^a	0.54 ± 0.01	0.57 ± 0.01

Values are expressed as mean ± SEM of 10 animals in each group. Results are significant compared to the untreated control group at ^a, ^b, and ^c.