In Vitro Evaluation of the Neuroprotective Effect of Panax notoginseng Saponins by Activating the EGFR/PI3K/AKT Pathway
Apoptosis and cytotoxicity of SH-SY5Y cells after treatment. The apoptosis rate is the sum of B2 and B4. (a) Following treatment with PNS and P + A, apoptosis rates were significantly reduced (). The apoptosis rate of the P + A group was significantly higher than that of the PNS group (). Values are expressed as the mean ± SEM (n = 3). vs. model group. vs. PNS group. (b) The bar graph represents the apoptosis rate of each group. (c) The bar graph shows the cytotoxicity of the five groups. In brief, PNS and P + A treatment reduced cytotoxicity of OGD SH-SY5Y cells compared with the model group (). The cytotoxicity of the P + A group was significantly enhanced compared with the PNS group (). Values are expressed as the mean ± SEM (n = 6). vs. model group. vs. PNS group.
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