Research Article

Antiplasmodial and Genotoxic Study of Selected Ghanaian Medicinal Plants

Table 1

IC50 of extracts on the growth of two laboratory strains of Plasmodium falciparum.

EXTRACTMean IC50 (µg/ml) of extracts on Dd2Mean IC50 (µg/ml) of extracts on 3D7 value

Acanthospermum hispidium DC3.70 ± 0.083.66 ± 0.060.70
Alstonia boonei (De Wild)3.62 ± 0.205.47 ± 0.020.79
Senna siamea Lam4.47 ± 0.113.95 ± 0.060.13
Murinda lucida Benth6.47 ± 0.125.50 ± 0.060.52
Phyllanthus niruri L5.74 ± 0.205.47 ± 0.020.57
Artesunate0.006 ± 0.00040.006 ± 0.00030.85

The table shows the IC50 of the various extracts. The results are presented as mean ± 2 standard deviations.