Research Article
Antiplasmodial and Genotoxic Study of Selected Ghanaian Medicinal Plants
Table 5
Genotoxic effect of the extracts on human peripheral mononuclear cells (PBMCs).
| Extract added (concentration, µg/ml) | Visual comet score (data set 1) | Visual comet score (data set 2) | Comet score (average) | % DNA in tail of comet |
| Control | 0 | 0 | 0 | 0 | A. hispidum (3.3) | 2 | 2 | 1.5 | 20 | A. hispidum (13.0) | 2 | 2 | 2 | 30 | A. hispidum (52.1) | 2 | 2 | 2 | 45 | A. hispidum (208.3) | 2 | 2 | 2 | 55 | A. hispidum (833.3) | 3 | 3 | 3 | 75 | Alstonia boonei (3.3) | 2 | 2 | 1.5 | 20 | Alstonia boonei (13.0) | 2 | 2 | 2 | 25 | Alstonia boonei (52.1) | 2 | 2 | 2 | 30 | Alstonia boonei (208.3) | 2 | 2 | 2 | 46 | Alstonia boonei (833.3) | 3 | 3 | 3 | 65 | Senna siamea Lam (3.3) | 2 | 2 | 1.5 | 20 | Senna siamea Lam (13.0) | 2 | 2 | 2 | 35 | Senna simea Lam (52.1) | 2 | 2 | 2 | 40 | Senna siamea Lam (208.3) | 2 | 2 | 2 | 55 | Senna siamea Lam (833.3) | 3 | 3 | 3 | 70 |
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