Antiplasmodial and Genotoxic Study of Selected Ghanaian Medicinal Plants

Table 5

Genotoxic effect of the extracts on human peripheral mononuclear cells (PBMCs).

Extract added (concentration, µg/ml)	Visual comet score (data set 1)	Visual comet score (data set 2)	Comet score (average)	% DNA in tail of comet
Control	0	0	0	0
A. hispidum (3.3)	2	2	1.5	20
A. hispidum (13.0)	2	2	2	30
A. hispidum (52.1)	2	2	2	45
A. hispidum (208.3)	2	2	2	55
A. hispidum (833.3)	3	3	3	75
Alstonia boonei (3.3)	2	2	1.5	20
Alstonia boonei (13.0)	2	2	2	25
Alstonia boonei (52.1)	2	2	2	30
Alstonia boonei (208.3)	2	2	2	46
Alstonia boonei (833.3)	3	3	3	65
Senna siamea Lam (3.3)	2	2	1.5	20
Senna siamea Lam (13.0)	2	2	2	35
Senna simea Lam (52.1)	2	2	2	40
Senna siamea Lam (208.3)	2	2	2	55
Senna siamea Lam (833.3)	3	3	3	70