Research Article
N-Butanol Extract of Gastrodia elata Suppresses Inflammatory Responses in Lipopolysaccharide-Stimulated Macrophages and Complete Freund’s Adjuvant- (CFA-) Induced Arthritis Rats via Inhibition of MAPK Signaling Pathway
Figure 1
Antiarthritic effect of different doses of BGE in complete Freund’s adjuvant-induced arthritis (CFA) rats. (a) Effects of different doses of BGE on hind paw swelling in CFA rats. Data were presented as mean ± SD (n = 8). (b) Effects of different doses of BGE on body weight changes in CFA rats. Data were presented as mean ± SD (n = 8). (c) Swelling manifestations in CFA rats after various treatments. Except normal group (Nor), CFA rats were treated daily with BGE at 25, 50, and 100 mg/kg·d−1, DEX at 0.4 mg/kg·d−1, or distilled water (CFA group) from day 14 after immunization. , compared with the normal group. , , compared with the CFA group.
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