Research Article

Topical Anti-Inflammatory Activity of Essential Oils of Alpinia calcarata Rosc., Its Main Constituents, and Possible Mechanism of Action

Figure 6

Effects of ACEOs on TPA-induced ear edema. Inhibition of TPA-induced ear edema by topical application of EO (5, 1, and 0.25%) was analyzed by measuring changes in ear thickness in millimeters (a), changes in ear weight in grams (b), and percentage inhibition of myeloperoxidase activity in tissue homogenates (c). N: normal; C: TPA-treated control group; RO: rhizome essential oil; LO: leaf essential oil; IMN: indomethacin at 0.5 mg/ear. Symbols “,” “,” “,” and “” represent a significant difference , , , and between TPA treatment and EO-treated animals. Symbol “” represents a significant difference between normal and TPA-treated groups.
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