Research Article

Topical Anti-Inflammatory Activity of Essential Oils of Alpinia calcarata Rosc., Its Main Constituents, and Possible Mechanism of Action

Table 2

Intracellular ROS inhibition, superoxide anion scavenging, and inhibition of heat-induced hemolysis by ACEOs.

TreatmentConcentration (μg/mL)RLU ± SEMInhibition of intracellular ROS (%)Superoxide inhibition (%)Inhibition of heat-induced hemolysis (%)

Normal298.53 ± 104.76

Control3587.56 ± 123.56

RO50568.9 ± 20.6784.16 ± 5.5613.45 ± 3.4572.12 ± 0.25
251305.76 ± 54.7663.51 ± 7.3410.54 ± 6.5656.34 ± 0.45
12.52135.98 ± 15.7840.46 ± 5.878.45 ± 7.3434.87 ± 0.76
6.252582.45 ± 30.9828.09 ± 6.346.44 ± 3.8922.56 ± 1.22
3.122902.23 ± 45.7618.65 ± 4.342.56 ± 6.7715.67 ± 2.34
1.563276.67 ± 46.328.67 ± 6.562.31 ± 1.4512.45 ± 0.23

LO50452.76 ± 67.2387.32 ± 2.3112.12 ± 3.2483.32 ± 0.34
251056.34 ± 59.5670.56 ± 1.1212.34 ± 1.1167.23 ± 0.76
12.51809.67 ± 23.3449.56 ± 2.452.46 ± 6.5754.09 ± 2.23
6.252598.43 ± 67.2327.57 ± 4.562.11 ± 1.3524.76 ± 0.34
3.122765.34 ± 25.6722.91 ± 2.232.56 ± 2.2314.65 ± 0.23
1.563015.56 ± 34.8715.98 ± 3.452.61 ± 2.4510.23 ± 0.45

Dexamethasone5 µM777.45 ± 34.5678.33 ± 2.562.56 ± 1.7791.77 ± 0.56

Data are mean ± SEM (n = 6). , significantly different from the normal group; , , and , significantly different from the control group. RO: rhizome EO; LO: leaf EO.