Topical Anti-Inflammatory Activity of Essential Oils of Alpinia calcarata Rosc., Its Main Constituents, and Possible Mechanism of Action
Table 2
Intracellular ROS inhibition, superoxide anion scavenging, and inhibition of heat-induced hemolysis by ACEOs.
Treatment
Concentration (μg/mL)
RLU ± SEM
Inhibition of intracellular ROS (%)
Superoxide inhibition (%)
Inhibition of heat-induced hemolysis (%)
Normal
298.53 ± 104.76
Control
3587.56 ± 123.56
RO
50
568.9 ± 20.67
84.16 ± 5.56
13.45 ± 3.45
72.12 ± 0.25
25
1305.76 ± 54.76
63.51 ± 7.34
10.54 ± 6.56
56.34 ± 0.45
12.5
2135.98 ± 15.78
40.46 ± 5.87
8.45 ± 7.34
34.87 ± 0.76
6.25
2582.45 ± 30.98
28.09 ± 6.34
6.44 ± 3.89
22.56 ± 1.22
3.12
2902.23 ± 45.76
18.65 ± 4.34
2.56 ± 6.77
15.67 ± 2.34
1.56
3276.67 ± 46.32
8.67 ± 6.56
2.31 ± 1.45
12.45 ± 0.23
LO
50
452.76 ± 67.23
87.32 ± 2.31
12.12 ± 3.24
83.32 ± 0.34
25
1056.34 ± 59.56
70.56 ± 1.12
12.34 ± 1.11
67.23 ± 0.76
12.5
1809.67 ± 23.34
49.56 ± 2.45
2.46 ± 6.57
54.09 ± 2.23
6.25
2598.43 ± 67.23
27.57 ± 4.56
2.11 ± 1.35
24.76 ± 0.34
3.12
2765.34 ± 25.67
22.91 ± 2.23
2.56 ± 2.23
14.65 ± 0.23
1.56
3015.56 ± 34.87
15.98 ± 3.45
2.61 ± 2.45
10.23 ± 0.45
Dexamethasone
5 µM
777.45 ± 34.56
78.33 ± 2.56
2.56 ± 1.77
91.77 ± 0.56
Data are mean ± SEM (n = 6). , significantly different from the normal group; ,, and , significantly different from the control group. RO: rhizome EO; LO: leaf EO.