Topical Anti-Inflammatory Activity of Essential Oils of Alpinia calcarata Rosc., Its Main Constituents, and Possible Mechanism of Action

Table 3

Effect of ACEOs on COX-1 enzyme activity.

Class	PGF2α(pg/mL)	Percentage of inhibition
Background tube	2.25 ± 0.75
COX-1 100% initial activity tube	221 ± 14.5
Rhizome EO
0.5 μg/mL	178 ± 4.5	19.45
5 μg/mL	158 ± 2.23	28.5
50 μg/mL	52 ± 5.23	76.47
Leaf EO
0.5 μg/mL	198 ± 5.45	10.4
5 μg/mL	161 ± 2.56	27.14
50 μg/mL	76 ± 2.12	65.61
Indomethacin
10 μg/mL	22 ± 3.45	90