Research Article
Topical Anti-Inflammatory Activity of Essential Oils of Alpinia calcarata Rosc., Its Main Constituents, and Possible Mechanism of Action
Table 4
Effect of ACEOs on COX-2 enzyme activity.
| Class | PGF2α (pg/mL) | Percentage of inhibition (%) |
| Background tube | 0.75 ± 0.1 | | COX-2 100% initial activity tube | 154 ± 4.5 | |
| Rhizome EO | | | 0.5 μg/mL | 121 ± 4.5 | 21.4 | 5 μg/mL | 98 ± 1.23 | 36.3 | 50 μg/mL | 22 ± 2.56 | 85.7 |
| Leaf EO | | | 0.5 μg/mL | 145 ± 2.78 | 5.84 | 5 μg/mL | 111 ± 1.54 | 27.92 | 50 μg/mL | 46 ± 1.12 | 70.12 |
| NS-398 | 4 ± 2.21 | 97.4 | 10 μmol/L | | |
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