Topical Anti-Inflammatory Activity of Essential Oils of Alpinia calcarata Rosc., Its Main Constituents, and Possible Mechanism of Action

Table 4

Effect of ACEOs on COX-2 enzyme activity.

Class	PGF2α (pg/mL)	Percentage of inhibition (%)
Background tube	0.75 ± 0.1
COX-2 100% initial activity tube	154 ± 4.5
Rhizome EO
0.5 μg/mL	121 ± 4.5	21.4
5 μg/mL	98 ± 1.23	36.3
50 μg/mL	22 ± 2.56	85.7
Leaf EO
0.5 μg/mL	145 ± 2.78	5.84
5 μg/mL	111 ± 1.54	27.92
50 μg/mL	46 ± 1.12	70.12
NS-398	4 ± 2.21	97.4
10 μmol/L