Lactobacillus Plantarum HFY15 Helps Prevent Retinoic Acid-Induced Secondary Osteoporosis in Wistar Rats

Figure 4

Pathological observation of rats’ femur and tibia stained with TRAP. Magnification: 100×. Normal: normal rats control; Model: rats treated with retinoic acid (80 mg/kg/d); Zoledronic Acid: rats treated with retinoic acid (80 mg/kg/d) and a single dose of 0.5 mL/100 g zoledronic acid; HFY15: rats treated with retinoic acid (80 mg/kg/d) and 1 mL/100 g with 10¹⁰ CFU/kg of Lactobacillus plantarum HFY15.